Nominator's project description
| Important traits in complex organisms are controlled by millions of DNA sequence variants which determine gene activity and interactions. However, the mechanisms of this process are still only poorly understood. Dr. Golicz is a bioinformatician who uses vast genome sequence datasets to investigate how plant genomes are organised and how genome organisation impacts gene and trait expression. During her PhD and postdoctoral research in Australia, she investigated the dynamics of genome evolution in different wild and crop plants. Now she aims to use new techniques to elucidate the role of 3-dimensional genome structure and “non-coding” DNA sequences on gene regulation. Using the complex genome of rapeseed as a model, her analyses will help understand and predict how functional sequence variants impact gene expression, evolution and performance in an important crop species. |
